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| Discussion on the role of albumin preparations in tumor nutritional therapy |
| 1Lyu Dapeng,2Mu Ying,3Cao Bingqing |
| 1Breast Center Beijing Shijitan Hospital Capital Medical University Beijing 100038 China
2
Surgery Department Peking University
Hospital Beijing 100871 China
3Respiratory Department Capital Institute Pediatrics Capital Medical University Beijing
100020 China |
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Abstract Patients with malignant tumors often suffer from malnutrition due to chronic energy-protein depletion insufficient intake
of other nutrients in the body and malabsorption resulting in energy and protein deficiency. Serum albumin level is an important
indicator to reflect the nutritional status of patients. Clinically albumin preparations are often mistakenly used as nutrients in clinical
practice. In fact the nutritional supply of cancer patients should be based on amino acids and energy supplementation. This article
analyzes the basic points of human nutritional requirements metabolic changes nutritional status classification and nutrient supply of
cancer patients. And we discussed the principles methods and classification of human nutrients and specific calculation methods of
dosage supply A variety of amino acid formulation types that can be provided clinically. The synthesis and distribution of albumin in
vivo were analyzed in detail. The main role of serum albumin in the human body is to expand blood volume and maintain plasma
osmolality and it also has the biological function of non-osmotic pressure. The application history of albumin preparations and the
clinical guidelines for albumin preparations in China and abroad are reviewed. The significance of albumin preparations in the
application of various diseases is mainly used in shock caused by trauma and burns edema and ascites caused by liver cirrhosis or
kidney disease cerebral edema neonatal hyperbilirubinemia. The misunderstandings of the clinical application of human albumin
preparations were analyzed. This article provides a theoretical basis for how to correctly provide nutrition for cancer patients and how to
use albumin preparations correctly and rationally.
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Received: 26 February 2024
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