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| The research progress of immunonutrients in the prevention and treatment of malignant tumors |
| Liu Xiangrong, Liu Yinghua |
| Department of Nutrition the First Medical Center of the Chinese People′s Liberation Army General Hospital Beijing 100853 China |
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Abstract With the deepening research on the immune mechanisms of malignant tumors the study and clinical application of
immunonutrients are continually advancing and innovating. A multitude of studies have shown that various immunonutrients can prevent
the occurrence of malignant tumors reduce resistance to certain chemotherapeutic drugs alleviate postoperative complications shorten
hospital stays and expedite recovery of immune function and nutritional status through mechanisms such as anti - inflammation
enhancement of immune cell functions inhibition of malignant tumor cell proliferation and metastasis as well as induction of tumor cell
apoptosis. However despite this extensive research there is currently no consensus on the preventive therapeutic and prognostic
roles of immunonutrients like glutamine arginine ω-3 polyunsaturated fatty acids and vitamins in the context of malignant tumors
due to the scarcity of large-scale high-quality evidence. This article aims to systematically review the mechanistic roles and clinical
efficacies of protein-based immunonutrients glutamine and arginine fatty acid-based immunonutrients ω-3 polyunsaturated fatty
acids micronutrients vitamins and selenium microecological immunonutrients synbiotics and plant extract - based
immunonutrients ginsenosides in the context of malignant tumor prevention and management. The objective is to explore the distinct
features and inherent limitations of these different categories of immunonutrients thereby providing a foundation and direction for
further in-depth research on the use of immunonutrients against malignant tumors and their integration into clinical practice.
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Received: 22 January 2024
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