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| Application study of cancer prehabilitation in overweight and obese patients with breast cancer undergoing radiotherapy |
| 1Tao Wei,2Wang Shu'an,1Jiang Chunyu,1Zhang Jianyu,1Qiao Xue,1Yu Jingyi,2Chen Xiaotian |
| 1Department of Radiotherapy Nanjing Pukou people's Hospital Nanjing 211800 Jiangsu China
2Department of Clinic Nutrition
Nanjing Drum Tower Hospital Affiliated Hospital of Nanjing University Medical School Nanjing 210008 Jiangsu China |
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Abstract Objective To explore the cancer prehabilitation CP concept for overweight or obese breast cancer BC auxiliary during
radiotherapy in patients with nutritional status the influence of the blood lipid metabolism and complications. Method A retrospective
study was conducted on 118 patients with BC who received adjuvant radiotherapy in the department of radiotherapy of Nanjing Pukou
People's Hospital from January 2020 to March 2022. They were divided into prehabilitation group n = 63 and control group n = 55 .
The indexes of HB ALB TG TC HDL - C LDL - C FACIT - F score JSEQ score radiation dermatitis and VAS score were
compared between the two groups. Result During radiotherapy the hemoglobin level of the two groups decreased without significant
difference P > 0. 05 . The serum albumin level of the prehabilitation group was better than the control group P < 0. 05 . In terms of
lipid metabolism the increase of TG in the prehabilitation group was lower than the control group P < 0. 05 while there was no
significant difference in TC HDL-C and LDL-C P > 0. 05 . FACIT-F score JSEQ score degree of radiation dermatitis and VAS score of
pain in the prehabilitation group were better P < 0. 05 . Conclusion In the adjuvant radiotherapy of overweight or obese BC patients CP
may not only help to maintain nutritional status and to improve lipid metabolism but also help to improve the related complications.
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Received: 02 April 2023
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