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| Effects of probiotics combined with enteral nutrition on postoperative inflammatory factors cellular immune function and
nutritional indexes in patients with gastric cancer undergoing radical operation |
| 1Li Zhou ，1Ma Yong ，1Fang Shixu ，2Xu Lin |
| 1Department of General Surgery Zigong First People's Hospital ZiGong 643000 Sichuan China
2Department of Gastrointestinal
Surgery Sichuan Cancer Hospital Chengdu 610041 Sichuan China |
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Abstract Objective To observe the effect of probiotics combined with enteral nutrition support on postoperative inflammatory
factors cellular immune function and nutritional indicators in patients with gastric cancer after radical operation. Method 134 patients
with gastric cancer who underwent laparoscopic assisted radical gastrectomy in general surgery department of Department of General
Surgery Zigong First People's Hospital from January 2020 to July 2022 were selected and randomly divided into control group n = 67
and observation group n = 67 The control group received early enteral nutrition support EENS group and the observation group
received probiotics combined with early enteral nutrition support PEENS group. The levels of inflammatory factors IL-2 IL-6
TNF - α cellular immune function CD4
+
CD8
+
CD4
+
/ CD8
+
and nutritional indexes albumin and total protein levels in
peripheral blood measured by protein analyzer and complications were compared between the two groups before and after
treatment. Result After the intervention the levels of IL-2 IL-6 and TNF - α in the observation group were significantly lower than
those in the control group and before the intervention P<0. 05
+
/ CD8
+
levels were significantly higher than those in the control group
and before intervention P<0. 05 CD8
+
levels in the observation group after intervention were significantly lower than those in the
control group and before intervention P < 0. 05 albumin and total protein levels in the observation group after intervention were
significantly higher than those in the control group and before intervention P < 0. 05 there was no significant difference in the
incidence of complications between the two groups P>0. 05 . Conclusion Probiotics can effectively reduce the level of inflammatory
response protect cellular immune function and improve nutritional status in patients with early gastric cancer after operation.
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Received: 20 July 2022
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| Cite this article: |
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1Li Zhou,1Ma Yong,1Fang Shixu, et al. Effects of probiotics combined with enteral nutrition on postoperative inflammatory factors cellular immune function and
nutritional indexes in patients with gastric cancer undergoing radical operation[J]. Electron J Metab Nutr Cancer, 2023, 10(2): 225-229.
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| URL: |
| http://182.92.200.144/EN/ OR http://182.92.200.144/EN/Y2023/V10/I2/225 |
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