Abstract：Objective To study the effects of parenteral nutrition support in patients with gastrointestinal cancer during the perioperative period of thyroid hormone and prealbumin (PA) levels. MethodsFrom May 2013 to July 2016, 80 cases with gastrointestinal cancer treated in our hospital were randomly divided into the observation group and the control group, with 40 cases in each group. The observation group was given parenteral nutrition support after operation, and the control group was not given parenteral nutrition support. The preoperative 1 day, postoperative 1 day, postoperative 5 days and thyroid hormone and PA levels in the two groups were detected before and after operation respectively in the patients of the two groups, respectively. The results showed that the patients in the control group were not given parenteral nutrition support after operation. The levels of thyroid hormone and 8 days in the two groups were detected before operation, after the operation, after the operation and after the operation.The particle analysis method for detecting free triiodothyronine three capture ELISA (FT3) and total three triiodothyronine (TT3), detection of reverse triiodothyronine three by radioimmunoassay (rT3) and the level of PA. The correlation analysis was done. ResultsThe observation group preoperative 1D, postoperative 1 day, postoperative 5 days and postoperative 8 days, FT3, TT3, rT3, PA level, using the analysis of variance of repeated measurement data, the results showed that: different time points of FT3, TT3, rT3, PA level differences were statistically significant (P<0.05).The control group preoperative 1D, postoperative 1 day, postoperative 5 days and postoperative 8 days, FT3, TT3, rT3, PA level, using the analysis of variance of repeated measurement data, the results showed that: different time points of FT3, TT3, rT3, no significant difference in PA levels (P>0.05). Pearson correlation analysis showed that the FT3, TT3 and PA levels in the observation group were positively correlated (r=0.473, P<0.01; r=0.502, P<0.01) at different time periods, while the rT3 and PA levels were negatively correlated (r=-0.424, P<0.05). ConclusionThe gastrointestinal cancer patients before the existence of non thyroid disease syndrome, and in a short period after operation can not be fully restored. In addition, parenteral nutrition support in patients with gastrointestinal cancer during the perioperative period of thyroid hormone and PA levels have obvious changes, can be used as one of the evaluation indexes of patients with perioperative nutritional status.
万莹. 胃肠道肿瘤患者围术期营养治疗对甲状腺激素及前清蛋白水平影响[J]. 肿瘤代谢与营养电子杂志, 2017, 4(4): 458-462.
WAN Ying. The level of thyroid hormone and albumin after nutrition supportive therapy in perioperative gastrointestinal cancer patients. Electronic Journal of Metabolism and Nutrition of, 2017, 4(4): 458-462.
