Abstract：Ketogenic diet was used in children to remedy epilepsy nearly 100 years. Such long history fully proved its safety and effectiveness. In the field of weight management, ketogenic diet had strong practicality, easy operation and long persistence. Due to the high fat diet in ketogenic diet existed cognitive bias with traditional nutrition knowledge, either theory or the of clinical practice needed standardized training. This paper introdused the background, biochemistry, indications, contraindications, adverse reactions of the ketogenic diet, as preliminary exposition and base, ready for co-authoring specialist consensus with other experts. Diet, exercise, or operation are frequency-used methods in loss weight by limiting energy intake or increasing energy consumption, while ketogenic diet was another mechanism differing these methods. Ketogenic diet simulated starvation by controlling carbohydrate intake, transforming triglyceride into ketone, then excreting ketone from the urine. Elevatory ketone also can suppress appetite to reduce food and energy intake. The indications of ketogenic diet were: BMI>28; with normal liver and kidney functions. Contraindications were patients whose lack functional key enzyme for fat metabolism, and failure of liver and kidney functions. Baseline assessment is necessary before initiating ketogenic diet, Blood and urine ketone should to be monitored during whole ketogenic diets loss procession.
