Research progress on the mechanism of mindful eating in obese patients
1Li Qingjiao,2Tang Lu,3Cai Hua
1Department of Rehabilitation Medicine Hunan Provincial People's Hospital The First Affiliated Hospital of Hunan Normal University
Changsha 410000 Hunan China
2
Interventional Vascular Surgery Hunan Provincial People's Hospital The First Affiliated Hospital of
Hunan Normal University Changsha 410000 Hunan China
3Department of Clinical Nutrition Hunan Provincial People's Hospital
The First Affiliated Hospital 0f Hunan Normal University Changsha 410000 Hunan China
Abstract：The global epidemic of obesity has underscored the critical need for innovative approaches to traditional intervention
strategies. Mindful eating intervention MEI an interdisciplinary approach integrating behavioral medicine and nutritional
psychology represents a promising paradigm for obesity management. This review systematically examines the multidimensional
mechanisms underlying MEI at the neurophysiological level MEI modulates metabolic homeostasis through the regulation of satiety
signaling pathways gastrointestinal motility and hormonal secretion while simultaneously enhancing dietary decision-making via the
inhibition of reward circuits activation of executive control networks and functional optimization of the insular cortex at the
psychological level MEI facilitates the differentiation between emotional states and physiological hunger thereby mitigating stressinduced hyperphagia. Future research directions should incorporate advanced methodologies including genomic profiling and virtual
reality-based interventions to facilitate the translation of MEI from theoretical frameworks to clinical applications thereby offering
comprehensive interdisciplinary solutions for the prevention and treatment of obesity.
