Abstract：Abstract: Objective The aim of this study was to investigate the nutritional risk in patients with advanced gastric cancer received chemotherapy, using nutritional risk screening 2002 (NRS 2002) and patient-generated subjective global assessment (PGSGA), and to determine the potential relationship between the nutritional statusand the chemotherapy-related toxicity. Methods A continuous approach was used to screen patients with advanced gastric cancer, the NRS2002, PG-SGA, laboratory test indicators and other methods were applied to evaluate the nutritional risk and malnutrition of patients, the differences between the two kinds of tools in the investigation results were compared, and the correlation between nutritional risks and traditional objective indicators were analyzed. Results A total of 71 patients completed the nutrition survey. NRS survey shows that the incidence of nutritional risk was 67.61%, the incidence of malnutrition in PG-SGA was 80.28%, there was statistical significance between the two (P<0.05).When group according to the assessment results of NRS 2002, BMI was significantly different between the non-nutritional risk group and the nutritional risk group; when group by PG-SGA score results, prealbumin, albumin and CRP was significantly different between the two kinds of groups, the related incidence of adverse reactions (neutrophils reduced I/II and weary I/II) of patients with the nutritional risk group after their chemotherapy is higher than that of the patients belonging to the non-nutritional risk group. Conclusions Both NRS 2002 and PG-SGA are applicable to the nutritional status investigation of patients with advanced gastric cancer, but the malnutrition detection rate of PG-SGA was higher, so it can assess the nutritional status of patients more effectively. The PG-SGA scale is recommended to carry out the comprehensive evaluation for advanced gastric cancer patients before chemotherapy, so as to better guide clinical nutrition therapy.
2016, Vol. 3 
