Abstract：Malnutrition is a prevalent clinical issue among gastrointestinal cancer patients contributing not only to impaired
immune function but also to diminished treatment efficacy delayed rehabilitation and poorer prognosis. The primary causes of
malnutrition include tumor - induced metabolic alterations insufficient dietary intake the release of inflammatory mediators and
adverse effects associated with radiotherapy and chemotherapy. In recent years psychological distress has emerged as significant
contributors to malnutrition warranting greater attention. The process of cancer diagnosis and treatment often triggers profound
psychological distress such as anxiety and depression. These psychological stresses may disrupt gastrointestinal function by impairing
nutrient intake and absorption. Furthermore tumor-related psychological distress compounded by visceral discomfort arising during
treatment frequently induces somatic symptoms such as anorexia fatigue nausea and abdominal distension. Patients may excessively
focus on these symptoms exacerbating emotional reactions further reducing food intake and intensifying malnutrition. Current
nutritional interventions for cancer patients primarily emphasize the supplementation of specific nutrients with insufficient attention
given to the impact of psychological factors. This paper explored the role of psychological distress in cancer - related malnutrition
through the lens of psychosomatic medicine. It underscored the necessity of adopting an integrated biopsychosocial medical model in
cancer care. Early identification and targeted intervention for psychological and emotional disturbances have the potential to significantly
enhance patients' nutritional status improve treatment outcomes and facilitate recovery. This approach provides novel insights and
directions for the comprehensive management of cancer patients.
基金资助:国家消化系统疾病临床医学研究中心临床应用研究课题
(NCRCDD2020-05)
通讯作者:
赵青川,电子邮箱:zhaoqc@ fmmu. edu. cn
引用本文:
赵治锋,赵青川. 重视消化道肿瘤患者心理困扰对其营养状态的影响[J]. 肿瘤代谢与营养电子杂志, 2025, 12(2): 143-147.
Zhao Zhifeng,Zhao Qingchuan. Impact of psychological distress on malnutrition in digestive cancer patient. Electron J Metab Nutr Cancer, 2025, 12(2): 143-147.
