The influence of multimodal pre-rehabilitation intervention based on the three-level diagnostic model of malnutrition on
patients with colorectal cancer
Liu Jianrong, Qi Bing, Yang Xueni, Deng Wenjuan, Zhou Miao, Chen Yulin, Wang Duo, Zou Hao, Liu Huiling
Department of Oncology the Second Affiliated Hospital of Xi'an Medical University Xi'an 710000 Shannxi China
Abstract：Objective Explore the impact of a multimodal pre-rehabilitation intervention based on a tertiary diagnostic model of
malnutrition on nutritional status gastrointestinal function and prognosis recovery in patients with colorectal cancer. Method
According to the inclusion and exclusion criteria 224 colorectal cancer patients collected from the Second Affiliated Hospital of Xi'an
Medical University between March 2021 and March 2024 were selected as the subjects of this study. Four of them were lost to
follow-up. The final prognosis of 220 colorectal cancer patients. Follow the principle of sealed envelope method conduct random
sampling for grouping it was divided into 2 groups. In the control group 110 patients were treated with a conventional rehabilitation
intervention the observation group of 110 patients underwent a multimodal pre-rehabilitation intervention based on a tertiary diagnostic
model of malnutrition. Two groups at 30 d after the intervention comparing the serum nutritional index physical and physical
examination gastrointestinal barrier function and quality of life scale QLQ - C30 scores at the same time the incidence of
postoperative complications during hospitalization was counted. Result After 30 d of corresponding intervention serum nutritional
index physical and physical examination results gastrointestinal barrier function and QLQ-C30 scores improved compared with the
same intervention P < 0. 05 . Comparing the two groups after intervention the improvement of Hb TP ALB DAO ET and
D-LAC at 30 d after intervention was better than the control group P <0. 05 BMI TSF AMC and QLQ-C30 score scores were
higher than the control group P <0. 05 and the postoperative complication rate 2. 73% vs 13. 64% was also lower than that of the
control group P <0. 05 . Conclusion Multimodal pre-rehabilitation based on the tertiary diagnostic model of malnutrition can improve
the postoperative intestinal barrier function and nutritional status of colorectal cancer patients reduce related complications and
improve the quality of life which has significant significance for postoperative recovery.
刘建荣,齐 冰,杨雪妮,邓文娟,周 苗,陈玉林,王 铎,邹 浩,刘会玲. 基于营养不良三级诊断模型的多模式预康复干预对结直肠癌患者的影响[J]. 肿瘤代谢与营养电子杂志, 2025, 12(1): 76-82.
Liu Jianrong, Qi Bing, Yang Xueni, Deng Wenjuan, Zhou Miao, Chen Yulin, Wang Duo, Zou Hao, Liu Huiling. The influence of multimodal pre-rehabilitation intervention based on the three-level diagnostic model of malnutrition on
patients with colorectal cancer. Electron J Metab Nutr Cancer, 2025, 12(1): 76-82.
