Cancer radiotherapy and nutritional therapy laying equal stress on basic nutrition and precision nutrition
Wu Han, Zhou Fuxiang
Department of Radiation and Medical Oncology Hubei Key Laboratory of Tumor Biological Behaviors Hubei Clinical Cancer Study
Center Zhongnan Hospital of Wuhan University Wuhan 430071 Hubei China
Abstract：Malnutrition is a common comorbidity and complication in cancer patients undergoing radiotherapy. It can reduce the
efficacy of radiotherapy increase adverse reactions to radiotherapy and even impact the patient 's survival time and quality of
life. Nutritional therapy is crucial for cancer patients undergoing radiotherapy and it is of great significance to provide standardized and
effective nutritional treatment for these patients. Nutritional therapy for cancer should be considered as first line and fundamental
treatment integrated throughout the entire process of cancer treatment. It is essential for cancer patients to undergo comprehensive
nutritional management throughout the "peri-radiotherapy period". Cancer is a metabolic disease and in addition to providing basic
nutritional therapy to meet the basic energy protein and nutrient needs of cancer patients personalized and precise nutritional therapy
should also actively explore aspects such as dietary regulation targeting tumor metabolism and immunonutrition. Cancer nutritional
therapy is not only about supplementing energy and nutrients but also about regulating cancer metabolism and immunity and even
improving survival rates. Both basic nutrition and precise nutritional therapy should be emphasized. Furthermore cancer patients
endure various psychological and physiological impacts during their treatment. Multimodal integrated rehabilitation can synergistically
enhance the patients' recovery making clinical rehabilitation integrated. Research is urgently needed to further explore the clinical
application of multimodal integrated rehabilitation based on nutritional therapy in radiotherapy patients through large-scale randomized
controlled trials.
