1Department of Oncology the Third Hospital of Wuhan / Tongren Hospital Affiliated to Wuhan University Wuhan 430061 Hubei China
2Department of Respiratory and Critical Care Medicine the Third Hospital of Wuhan / Tongren Hospital Affiliated to Wuhan University
Wuhan 430061 Hubei China
Abstract：Objective To explore the effects of medical customized diet HDMTM on nutritional status fatigue and quality of life
in patients with metastatic lung cancer. Method A prospective selection of 108 patients with metastatic lung cancer admitted to Wuhan
Third Hospital between June 2021 and June 2023 was conducted. They were randomly divided into two groups using a random number
table method. The control group 54 cases received routine nutritional support while the intervention group 54 cases received
HDMTM support. After intervention the nutritional status of the two groups serum albumin ALB total protein TP hemoglobin
Hb lung function forced expiratory volume in one second FEV1
forced vital capacity FVC maximum ventilation volume per
minute MVV cancer - related fatigue score and lung cancer specific quality of life assessment FACT - L score were
compared. Result After 14 days of intervention the nutritional status and lung function of the two groups of patients improved
compared to before treatment. The cancer-related fatigue score decreased and the FACT-L score increased with statistical significance
P<0. 05 . After 14 days of intervention the improvement of FEV1
92. 84 ± 4. 52 % MVV 91. 29 ± 5. 45 L/ min FVC 3. 55 ±
0. 39 L Hb 111. 12 ± 6. 57 g / L ALB 43. 11 ± 4. 58 g / L and TP 69. 78 ± 3. 16 g / L in the intervention group was better
than that in the control group with statistical significance P<0. 05 . The scores of emotional fatigue 4. 85 ± 1. 22 behavioral
fatigue 3. 13 ± 1. 52 physical fatigue 3. 38 ± 1. 19 and cognitive fatigue 3. 15 ± 1. 14 after 14 days of intervention were lower
than those of the control group with statistical significance P< 0. 05 . The FACT-L score 82. 85 ± 5. 25 and FACT-L score
93. 35 ± 4. 25 after 7 days of intervention were higher than those of the control group with statistical significance P< 0.05. Conclusion HDMTM is more targeted and scientific. Compared to conventional nutritional support it has a more significant effect in
patients with metastatic lung cancer. It can not only improve lung function and nutritional status promote disease recovery but also
alleviate fatigue improve quality of life and have higher utilization value.
1卢 英,1刘 柳,1杨思思,1韩慧敏,1舒文文,2徐建群. 医学定制膳食对转移性肺癌患者营养状况及生活质量的
影响[J]. 肿瘤代谢与营养电子杂志, 2024, 11(3): 396-401.
1Lu Ying,1Liu Liu,1Yang Sisi,1Han Huimin,1Shu Wenwen,2Xu Jianqun. Effect of medical custom diet on nutritional status and quality of life in patients with metastatic lung cancer. Electron J Metab Nutr Cancer, 2024, 11(3): 396-401.
