The modified patient-generated subjective global assessment can be used for the assessment of malnutrition in patients with
primary liver cancer
1Su Wenyi,2Li Bo,1Jiang Qilan,1Han Ming,1Liao Xin,1Wang Min
1Department of Clinical Nutrition the Affiliated Hospital of Southwest Medical University Luzhou 646000 Sichuan China
2Department of Hepatobiliary Surgery the Affiliated Hospital of Southwest Medical University Luzhou 646000 Sichuan China
Abstract：Objective To evaluate the nutritional status of patients with primary liver cancer and to compare the ability of
PG-SGA and mPG-SGA to assess malnutrition. Method Clinical data of 249 patients diagnosed with primary liver cancer for the first
time at Affiliated Hospital of Southwest Medical University between April 2022 and September 2023 were collected. PG-SGA and
mPG-SGA were used to assess the nutritional status of patients. Spearman correlation analysis was used to compare the correlation
between different nutritional indicators and two scales. The ROC curve was used to evaluate the accuracy of mPG-SGA. The Kappa
coefficients were used to evaluate the concordance between two scales. Result Among 249 patients with primary liver cancer 196
78. 71% and 189 75. 90% were diagnosed with moderate to severe malnutrition using PG - SGA and mPG - SGA
respectively. Using PG-SGA as a criterion mPG-SGA showed good accuracy for good / mild malnutrition moderate malnutrition and
severe malnutrition with AUC values of 0. 982 0. 938 and 0. 977 respectively P < 0. 001 . It also showed almost perfect
consistency with PG-SGA Kappa = 0. 951 P<0. 001 . Analysis by gender age history of smoking alcohol consumption clinical
stage and body mass index BMI subgroups revealed that mPG-SGA showed strong consistency for good / mild malnutrition moderate
malnutrition and severe malnutrition among patients with BMI < 18. 5 kg / m
2
Kappa = 0. 762 P = 0. 001 . All subgroups with the
exception of BMI<18. 5 kg / m
2
showed almost perfect consistency for the three different nutritional stages Kappa>0. 9 P<0. 001 .
Conclusion Malnutrition is prevalent in patients with primary liver cancer. mPG-SGA has been shown to have good accuracy and
concordance with PG-SGA. It is a simpler tool for assessing malnutrition in patients with primary live cancer.
1苏文意,2李 波,1姜祺澜,1韩 明,1廖 欣,1汪 敏. 改良版患者主观整体评估可用于原发性肝癌患者营养
不良的评估[J]. 肿瘤代谢与营养电子杂志, 2024, 11(3): 360-366.
1Su Wenyi,2Li Bo,1Jiang Qilan,1Han Ming,1Liao Xin,1Wang Min. The modified patient-generated subjective global assessment can be used for the assessment of malnutrition in patients with
primary liver cancer. Electron J Metab Nutr Cancer, 2024, 11(3): 360-366.
